Everquest Online Adventures has recently added the option to become infeceted with Lycanthropy to the game. Players can become one of five were races (werewolf, werebear, wererat, werelion, or weregator). Infection grants massive stat bonuses, opens up new options for character development, and carries heavy faction penalties in many good and neutral settlments.
Also recently implememted is the ability to train as a Were-hunter. Details are sketchy at this point, but it seems to be a new suite of abilities and character development options for any character that chooses not to become infected with lycanthropy.
There have also been many recent character balance additions to the game. You can get more information about Lycanthropy at the official site.