I recently purchased the first season of Sanctuary (starring Amanda Tapping of Stargate SG-1 fame) from the iTunes store. The season only had 13 episodes and priced at $25.87. The series tells of the story of Dr. Helen Magnus (Amanda Tapping) who operates a secret institution called "Santuary for all". Their purpose is to locate strange beings and creatures in order to help them and give them sanctuary but also to contain them if they are highly dangerous. Many of their charge comes willingly and lives in the large estate but some highly dangerous creature must first be captured and sedated by their retrieval team which is composed of Dr. Magnus' daughter Ashley (Emilie Ullerup) and the staffs and associates of the institution. The series deals with themes such as personal freedom for many of these often unslightly creatures/beings which have no way to integrate into normal society.
The first impression I had was, "Hey this series had Amanda Tapping on it so it should be good." After watching 2 more episodes my impression was "Hey, this IS good." As the episodes progressed a lot was revealed piece by piece about Dr. Helen Magnus, her history and the reason why she is doing this. Each episode is somewhat a self contained episode with a "monster of the week" theme. I think once the series has picked up steam they should switch to an over arching storyline because monster of the week can only go so far before getting old. And yes, there's an archnemesis for "Sanctuary for all" a shady organization called Cabal that seems to be intent on doing the same thing as Sanctuary, which is to locate strange beings/creatures and capture them but their purpose instead is to press/enslave these powerful creatures/beings into their service for their own gain. Everyone loves a good nemesis.
Do I recommend this series to anyone? Yes, but watch it with an open mind as there are only a few episodes released (Season 1 only has 13 episodes and Season 2 has 3 out as of this writing). I find this series thoroughly enjoyable with equal amounts of action and mystery.